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What is Low Dose Naltrexone (LDN)?
Naltrexone was approved by the FDA in the USA in the 1980s for the treatment of opioid addiction, used at the standard dose of 50 mg to 100 mg per day. It is a pure antagonist at various opioid receptors, Delta Kappa, Mu, and Opioid Growth Factor (OGF) receptors. LDN is not controlled medicine, narcotic, or an opioid.
Low Dose Naltrexone binds to the endorphin receptors for about 1–1/2 hours, and the blockade lasts about 4–6 hours. The effects of LDN are analgesia and anti-inflammatory. One of the other effects is that it increases the production of your own endorphins.
Source: LDN Research Trust
Why “Low Dose”?
When we talk about low dose naltrexone, we mean doses that are a 10th or less of the standard dose of Naltrexone. Most of the research studies have used 4.5 mg per day. Doses range from 0.001 mg–16 mg in clinical practice.
At the low dosage level, naltrexone exhibits paradoxical properties, including analgesia and anti-inflammatory actions, which have not been reported at larger dosages.
Source: Clinical Rheumatology
Who Might Benefit from LDN?
There is an emerging interest in patients seeking nontraditional treatment options for managing their chronic pain. Opioid addiction has long been an issue with pain management, pushing more patients to find alternatives with lower risks.
“Low dose naltrexone (LDN) is a novel therapy which may fulfill the “4 L’s” that many patients look for when using nontraditional therapies: low risk, low side effect profile, low dose, and low cost.”
Source: Practical Pain Management
The possible benefits of Low Dose Naltrexone can branch into addressing several conditions that are related to inflammation. For example:
- Autoimmune Conditions
- Ear, Nose, Throat
- Infectious Disease
- Ocular (Eyes)
- Veterinary (Pets)
- Women’s Health
Where Do I Get Low Dose Naltrexone (LDN)?
A prescription is required by your physician in order to get Low Dose Naltrexone (LDN). You cannot purchase LDN over-the-counter. LDN is specially formulated by compounding pharmacists that work with you and your medical provider to address specific symptoms.
Where Do I Start: LDN Consultations
Interested in learning more or getting a prescription for Low Dose Naltrexone (LDN)? Our LDN Experts at Eastern State Compounding Pharmacy are happy to assist you with any questions you may have regarding using LDN to address your health needs. Feel free to have your physician contact us directly for questions regarding the process of writing an rx prescription order for LDN.
If you have any additional questions for a pharmacist, would like to schedule a consultation, please contact us via the HIPAA compliant form below or by calling us at 800-964-0094