Low Dose Naltrexone (LDN): A Non-Opioid Option to Address Pain & Autoimmune Issues

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There has been a serious epidemic that has hit our society with respect to the abuse of opioid pain medication. Addiction is a real danger, which has led medical practitioners and their patients to turn to other alternatives in pain management.

Low dose naltrexone, also referred to as LDN is a non-opioid alternative for addressing chronic pain and autoimmune conditions. Positive results bring improved quality of life, and allow some relief for sufferers that have been searching for solutions.

What is Low Dose Naltrexone (LDN)?

Today, when we discuss low dose naltrexone, we mean doses that are a 10th or less of the standard dose of Naltrexone. Most of the research studies have used 4.5 mg per day. Doses range from 0.001 mg to 16 mg in clinical practice.

However, Naltrexone or Naltrexone HCL is only available commercially in 50-mg doses, whereas low-dose naltrexone (LDN) is usually prescribed at 4.5 mg or lower. 

This is where our expert LDN pharmacists play a role. We custom compound naltrexone powder depending on the prescription strength, dosage, and other factors.

Patients and their medical practitioners love the freedom to choose the form of medication that works best for their situation. LDN can be specially compounded into tablets, capsules, troches or lozenges, transdermal creams, oral liquids, and more.

Who May Benefit from Low Dose Naltrexone?

As the off-label use of LDN has gained popularity, it has been widely accepted as an alternative medicine option and is used to address various medical conditions.  These off-label conditions include:  

  • Multiple Sclerosis
  • Complex Regional Pain Syndrome
  • Fibromyalgia
  • Crohn’s Disease
  • Gastrointestinal Disorders
  • Cancer
  • Skin Conditions
  • Autism
  • Inflammatory Bowel Disease
  • …and more.
Low Dose Naltrexone (LDN) Requires a Prescription from your Doctor.

Why Choose Eastern States Compounding for LDN

We value quality, precision, and accountability and are proud to be pioneers in compounding. In March 2008, Eastern States Compounding Pharmacy became the first pharmacy in New England to earn national accreditation for both sterile and non-sterile compounding.

Every six months, our clean room, ante room, and laminar flow hood are tested and certified to comply with USP <797> standards. We conduct routine environmental monitoring, and our finished products are sent to an outside lab to be tested for sterility and potency.

    Get the LDN Info You Need

    If you are a prescriber, interested in offering your patients non-opioid options for addressing chronic pain or autoimmune issues, our expert pharmacists are free to answer your questions, provide education, consultation, or help in any way possible.

    If you are a patient interested in the potential alternative, please schedule a consultation or ask your doctor about Low Dose Naltrexone (LDN)

    Contact Us


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